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Foundations of Interventional Pain Management and Pain Medicine
TABLE OF CONTENTS
Contents
About the Editors xviii
Contributors xx
SECTION I
GENERAL ASPECTS
I-1.0 History of Specialty of Pain Medicine and Interventional Pain Management 1
Laxmaiah Manchikanti, MD, Vijay Singh, MD, Joshua A. Hirsch, MD
I-2.0 Education, Training, and Testing 13
Laxmaiah Manchikanti, MD, Vijah Singh, Md, Mark V. Boswell, MD, PhD
I-3.0 Epidemiology 27
Laxmaiah Manchikanti, MD, Vijay Singh, MD, Bert Fellows, MA
I-4.0 Review of Epidemiology of Chronic Pain 39
Laxmaiah Manchikanti, MD, Vijay Singh, MD, Bert Fellows, MA
I-5.0 Psychosocial and Cultural Aspects of Pain 55
Laxmaiah Manchikanti, MD, Bert Fellows, MA
I-6.0 Sex and Gender Issues in Pain 67
Laxmaiah Manchikanti, MD, Lien Tran, MD, Alan D. Kaye, MD, PhD
I-7.0 Neurophysiologic Basis and Diagnosis of Chronic Spinal Pain 81
Laxmaiah Manchikanti, MD, Ramsin M. Benyamin, MD,
Ricardo Vallejo, MD, Joshua A. Hirsch, MD
I-8.0 Assessment and Psychology of Pain 97
Laxmaiah Manchikanti, MD, Bert Fellows, MA
I-9.0 Mechanisms of Nociceptive Transmission and Modulation 123
James Giordano, PhD, Mark V. Boswell, MD, PhD
I-10.0 Pharmacology of Pain Transmission and Modulation 141
Sukdeb Datta, MD
I-11.0 Development of Pain Systems 153
Helen W. Karl, MD
SECTION II
EVIDENCE-BASED MEDICINE
II-1.0 Evidence-Based Medicine: Basic Concepts 165
Laxmaiah Manchikanti, MD, Joshua Hirsch, MD, Bert Fellows, MA
II-2.0 Critical Analysis of Literature 177
Laxmaiah Manchikanti, MD, Frank J.E. Falco, MD, Joshua A. Hirsch, MD
II-3.0 Principles of Valid Clinical Research and Components of Clinical Trials 207
Laxmaiah Manchikanti, MD, Joshua A. Hirsch, MD, Bert Fellows, MA
II-4.0 Special Features of Study and Analysis of Pain 231
Laxmaiah Manchikanti, MD, Bert Fellows, MA
SECTION III
ETHICS
III-1.0 Ethics of Pain Management and Research 243
Gail A. Van Norman, MD
III-2.0 Professionalism and Quality Assurance 257
Laxmaiah Manchikanti, MD, Frank J.E. Falco, MD, Joshua A. Hirsch, MD
III-3.0 Ethical Standards in Medical Practice 269
Gail A. Van Norman, MD
III-4.0 Placebo and Pain 279
Laxmaiah Manchikanti, MD, Joshua A. Hirsch, MD, Bert Fellows, MA
III-5.0 Animal Models of Pain 295
Sukdeb Datta, MD
SECTION IV
DIAGNOSIS
IV-1.0 Radiology 307
Frank J.E. Falco, MD, Obi Onyewu, MD, Syed Husain, DO
IV-2.0 Fluoroscopy 319
Frank J.E. Falco, MD, Obi Onyewu, MD, Syed Husain, DO
IV-3.0 MRI, fMRI, and MR spectroscopy 333
Obi Onyewu, MD, Frank J.E. Falco, MD, Syed Husain, DO
IV-4.0 Positron Emission Tomography (PET) Scans 343
Obi Onyewu, MD, Frank J.E. Falco, MD, Michael Greene, DO
IV-5.0 Ultrasound 349
Frank J.E. Falco, MD, Obi Onyewu, MD, Oluseun A. Olufade, MD
IV-6.0 Electrical Nerve Stimulation as a Diagnostic Tool 359
Virtaj Singh, MD, Jacob Joseph, MD, Kevin Hakimi MD
IV-7.0 Laser-Evoked Potentials 367
Frank J.E. Falco, MD, Gabriella Gutman, MD
IV-8.0 Quantitative Sensory Testing: Uses and Limitations 373
Nirupa Shah, MD, Andrea M. Trescot, MD
IV-9.0 Electroencephalography (EEG) & Magnetoencephalography (MEG) 379
Obi Onyewu, MD, Frank J.E. Falco, MD, Jignyasa Desai, DO
IV-10.0 Laboratory Investigations 389
ANDrea M. Trescot, MD
IV-11.0 Urine Drug Testing in Chronic Pain 399
Paul J. Christo, MD, Laxmaiah Manchikanti, MD, Xiulu Ruan, MD
IV-12.0 Psychological and Psychiatric Evaluation 415
Daniel Krashin, MD, Fadi al-hatem, MD
SECTION V
PRACTICE MANAGEMENT
V-1.0 Diagnostic Coding Systems 433
Laxmaiah Manchikanti, MD, Vijay Singh, MD, Bert Fellows, MA
V-2.0 Procedural Coding Systems 441
Laxmaiah Manchikanti, MD, Vijay Singh, MD
V-3.0 Documentation for Evaluation and Management Services 455
Laxmaiah Manchikanti, MD, Ramsin M. Benyamin, MD
V-4.0 Documentation for Interventional Techniques 471
Laxmaiah Manchikanti, MD, Vijay Singh, MD, Joshua A. Hirsch, MD
V-5.0 Compliance 487
Vicki Myckowiak, JD
SECTION VI
PHARMACOLOGICAL ASPECTS
VI-1.0 Opioids 499
Andrea M. Trescot, MD
VI-2.0 Antipyretic Analgesics: Nonsteroidals, Acetaminophen, and
Phenazone Derivatives 515
Bryan S. Williams, MD, and Paul J. Christo, MD
VI-3.0 Antidepressants 523
Howard S. Smith, MD, Laxmaiah Manchikanti, MD
VI-4.0 Anticonvulsants 533
Frank JE Falco, MD, Sareta M. Coubarous, DO, Oluseun A. Olufade, MD
VI-5.0 Anti-anxiety Agents 543
Charles Fox, MD, Henry Liu, MD, Alan D. Kaye, MD, PhD
VI-6.0 Neuroleptic Drugs 553
Ryan P. Ellender, MD, Alan D. Kaye, MD, PhD, Adam M. Kaye Pharm D
VI-7.0 Antihistamines 559
Judy G. Johnson MD, Adam J. Broussard, MD, Alan D. Kaye, MD, PhD
VI-8.0 Analeptic Drugs 571
Frank J.E. Falco, MD, Sareta M. Coubarous, DO
VI-9.0 Corticosteroids 589
Laxmaiah Manchikanti, MD and VIjay Singh, MD
VI-10.0 Muscle Relaxants and Antispasticity Drugs 607
M. Tyler Stout, MD, Alan D. Kaye, MD, PhD, Adam M. Kaye, PharmD
VI-11.0 NMDA Receptor Antagonists 615
Brad J. Hymel MD, Alan D. Kaye, MD, PhD, Adam M. Kaye, PharmD
VI-12.0 Local Anesthetics and Membrane-Stabilizing Drugs 623
Stephen M. O’Connell, DO, Andrea M. Trescot, MD
VI-13.0 Sympatholytics 635
Sheila Chiu, DO
VI-14.0 Adjuvant Analgesics 641
Mariam Hameed, MD, Haroon Hameed, MD and Steven P. Cohen, MD
Index 667
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